Larry R. Brown,Kimberly A. Gillis,Michael V. Gallo
申请号:
US12105213
公开号:
US08808747B2
申请日:
2008.04.17
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present disclosure is related to microparticle compositions, in which the microparticles are made of nucleic acids and non-polymeric cations, which are suitable for administration to moist or aqueous target locations (e.g., the lung tissue), where the substantially spherical nucleic acid microparticles release the nucleic acids through dissolution, allowing the released nucleic acids to freely interact with the target cells.