Compositions and methods for nanopolymer-based nucleic acid delivery

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专利权人:

Inc.;Marine Polymer Technologies

发明人:

Vournakis, John N.,Demcheva, Marina V.

申请号：

AU2011323078

公开号：

AU2011323078B2

申请日:

2011.11.07

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

Provided herein are p-GlcNAc nanoparticle/nucleic acid compositions. In one aspect, the p-GlcNAc nanoparticle/nucleic acid compositions comprise deacetylated poly-N- acetylglucosamine lactate derivative nanoparticles less than 500 nm and a nucleic acid. Also, provided herein are methods for administering a nucleic acid to a subject, the method comprising administering to the subject a p-GlcNAc nanoparticle/nucleic acid composition. In certain embodiments, the p-GlcNAc nanoparticle/nucleic acid composition is administered subcutaneous ly to the subject.

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