Analogs for CLR/RAMP receptor ligands are provided that have agonist, superagonist, antagonist or superantagonist activity. The analogs can be selective for one or more CLR/RAMP receptors, or can be pan-specific.提供CLR/RAMP受體配體之類似物,其具有促效劑、超促效劑、拮抗劑或超拮抗劑活性。該類似物對一或多種CLR/RAMP受體可具選擇性或可具泛特異性(pan-specific)。