PROBLEM TO BE SOLVED: To provide depression alleviation liquids and cosmetics as new applications using the characteristics of oxygen water.SOLUTION: The present invention provides depression alleviation liquids and cosmetics comprising, as an active ingredient, oxygen water which keeps the dissolved oxygen concentration equal to or greater than 25 ppm for 35 days or more under an open atmosphere, and has a specific gravity of 1.0001-1.0008.【課題】酸素水の特徴を利用した新しい用途として、うつ病緩和液および化粧料を提供すること。【解決手段】解放された大気下において、溶存酸素濃度が25ppm以上の状態が35日以上持続し、かつ、比重が1.0001~1.0008である酸素水を有効成分とする。【選択図】なし