The present invention relates to be used for the treatment of the compositions and the method for the spine structure that comprises vertebral body.In one embodiment, being used for promoting the osteoplastic method of vertebral body to comprise provides the compositions that comprises PDGF solution and biocompatible matrix, and comprises described compositions is administered at least one vertebral body.According to some embodiment, promote that the bone formation in the vertebral body can increase bone volume, quality and/or density, cause mechanical strength increase with the vertebral body of present composition treatment.
