Optimized monoclonal antibodies against tissue factor pathway inhibitor (TFPI)

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专利权人:

Bayer HealthCare LLC

发明人:

Wang, Zhuozhi,Pan, Junliang,Grudzinska, Joanna,Votsmeier, Christian,Tebbe, Jan,Birkenfeld, Joerg,Wobst, Nina,Bruckner, Simone,Stenig, Susanne

申请号：

AU2016269554

公开号：

AU2016269554B2

申请日:

2016.12.09

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2016269554B220181220.pdf#####Optimized Monoclonal Antibodies against Tissue Factor Pathway Inhibitor (TFPI) Abstract Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) are provided. Isolated nucleic acid molecules encoding monoclonal antibodies that bind TFPI are also contemplated. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided. H: fmt Interwoven NRPortbl DCC FMT 123336731 .docx - 9/12/16

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中国工程科技知识中心

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