Use of bisphosphonates as HIV / AIDS adjuvant therapy

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专利权人:

ズーリー ホールディングス リミテッド;オレゴン ヘルス アンド サイエンス ユニバーシティー

发明人:

リヒター、ヨラム,ゴロム、ガーション,サシャ、ヨナ、ビー．

申请号：

JP2016567549

公开号：

JP6592751B2

申请日:

2015.05.15

申请国别(地区):

JP

年份:

2019

代理人:

摘要：

The present invention relates to use of bisphosphonate formulations for the treatment and management of HIV/AIDS. The method of the invention comprises administering a formulation comprising an effective amount of a bisphosphonate that specifically inhibits the activity and/or decreases the number of monocytes and/or macrophages, thereby reducing or eliminating HIV reservoirs. The invention also provides a method of complementing an HIV antiviral therapy, such as the highly active antiretroviral therapy (HAART), with a bisphosphonate formulation to improve clinical outcome.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/