Treatment of cancer with heterocyclic inhibitors of glutaminase

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专利权人:

CALITHERA BIOSCIENCES INC.

发明人:

申请号：

IL23903215

公开号：

IL239032D0

申请日:

2015.05.27

申请国别(地区):

IL

年份:

2015

代理人:

摘要：

The invention relates to novel heterocyclic compounds and pharmaceutical preparations thereof and the methods of treating or preventing cancer using the compounds of the invention. Other aspects relate to methods of identifying a cancer patient that may benefit from treatment with a glutaminase inhibitor comprising determining the ratio of glutamate to glutamine, the ratio of glutaminase enzyme to glutamine synthetase or glutaminase activity in cancer cells of the patient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/