Emory University;Georgia Tech Research Corporation
发明人:
Mark R. Prausnitz,Bryce Chiang
申请号:
US16318804
公开号:
US20190240336A1
申请日:
2017.07.20
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided herein are fluid formulations for administration to a suprachoroidal space of an eye of a patient. The fluid formulations may include a pharmaceutical agent, a binding molecule, or a combination thereof. The pharmaceutical agent and the binding molecule may be bonded to each other covalently, non-covalently, or a combination thereof. The pharmaceutical agent may be configured to bond to an ocular tissue. The binding molecule may be configured to bond to an ocular tissue. Methods of administering the fluid formulations, methods of expanding a suprachoroidal space, and methods of reducing the minimum force to separate the sclera and choroid are provided.