PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PERAMPANEL

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专利权人:

MAPI PHARMA LTD.

发明人:

Ehud MAROM,Shai RUBNOV

申请号：

US15543363

公开号：

US20180008584A1

申请日:

2015.02.17

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention describes a process for the synthesis of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-di-hydro-pyridin-2-one (Perampanel) represented by the structure of formula (1), and salts thereof, especially salts with pharmaceutically acceptable acids. The present invention further relates to certain intermediates formed and/or used in such process.

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