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Recombinant attenuated parvovirus
专利权人:
Intervet International B.V.
发明人:
Spibey, Norman
申请号:
AU2011222910
公开号:
AU2011222910A1
申请日:
2011.03.03
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention is in the field of virus vaccines for protecting animals against infection by parvovirus, their production and use. More in particular, the invention is related to a vaccine comprising an attenuated parvovirus comprising a capsid protein or fragment thereof derivable from another parvovirus. Surprisingly it was found that such a vaccine was capable of inducing higher titers of protecting antibodies against a challenge with the second type of parvovirus strains while maintaining good immunity against the first type of parvovirus. Recombinant virus strains also remained attenuated.
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