ХЭГЕР Джеффри Х. (US),ДЖОЗЕФ Джеймс Д. (US),ЦЯНЬ Цзин (US),СМИТ Николас Д. (US),ЧОУ МАНЕВАЛ Эдна (US),РОЙЧОУДХАРИ Дебашиш Ф. (US),ФРИДМАН Лори (US),САМПАТ Дипак (US)
申请号:
RU2016137150
公开号:
RU2016137150A
申请日:
2015.03.12
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. Also described herein are methods of treating hormone resistant-estrogen receptor (ER) positive breast cancers characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator.