Opioid receptor antagonists

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专利权人:

ELI LILLY AND COMPANY

发明人:

CHAPPELL, MARK,MITCH, CHARLES,QUIMBY, STEVEN,SIEGEL, MILES

申请号：

ES05724297

公开号：

ES2379362T3

申请日:

2005.03.02

申请国别(地区):

ES

年份:

2012

代理人:

摘要：

A compound selected from the group consisting of: 4- [4- (2-Methylamino-ethyl) -phenoxy] -phenol, 4- {4- [2- (benzyl-methyl-amino) -ethyl] -phenoxy} -phenol , Acetic acid 4- [4- (2-benzylamino-ethyl) -phenoxy] -phenyl ester, 6- [4- (benzylamino-methyl) -phenylsulfanyl] -nicotinamide, 6- {4- [(3-methyl-] butylamino) -methyl] -phenylsulfanyl} -nicotinamide, 6- {4- [(2-pyridin-4-yl-ethylamino) -methyl] -phenylsulfanyl} -nicotinamide, 6- [4- (phenethylamino-methyl) -phenylsulfanyl] -nicotinamide, 6- {4- [(cyclopropylmethyl-amino) -methyl] -phenylsulfanyl} -nicotinamide, 6- {4- [(2-thiophene-2-yl-ethylamino) -methyl] -phenylsulfanyl} -nicotinamide, 6 - {4- [(3-phenyl-propylamino) -methyl] -phenylsulfanyl} -nicotinamide, 6- {4- [(3-methyl-butylamino) -methyl] -phenylsulfanyl} -nicotinamide, 4- [4- (phenethylamino -methyl) -benzenesulfonyl] -benzamide, 4- [4- (phenethylamino-methyl) -benzenesulfinyl] -benzamide, 6- [4- (2-benzylamino-ethyl) -phenylamino] -nicotinamide, 6- {4- [2 - (cyclohexylmethyl-amino) -ethyl] -phenylamino} -nicotinamide, 6- {4- [(2-pyridin-4-yl-ethylamm ino) -methyl] -phenylsulfanyl} -nicotinamide, 6- [4- (benzylamino-methyl) -phenylamino] -nicotinamide, 6- {4- [(cyclohexylmethyl-amino) -methyl] -phenylamino} -nicotinamide, 6- [ 4- (phenethylamino-methyl) -phenylamino] -nicotinamide, 6- {4- [(3-methyl-butylamino) -methyl] -phenylamino} -nicotinamide, N- {4- [4- (2-benzylamino-ethyl) -phenoxy] -phenyl} -acetamide, N- {4- [4- (2-hexylamino-ethyl) -phenoxy] -phenyl} -acetamide, N- [4- (4- {2- [(thiophen-2- ilmethyl) -amino] -ethyl} -phenoxy) -phenyl] -acetamide, N- (4- {4- [2- (3-phenyl-propylamino) -ethyl] -phenoxy} -phenyl) -acetamide, N- ( 4- {4- [2- (2-Cyclohexyl-ethylamino) -ethyl] -phenoxy} -phenyl) -acetamide, N- {4- [4- (2-phenethylamino-ethyl) -phenoxy-phenyl} -acetamide, N- {4- [4- (2-Propylamino-ethyl) -phenoxy] -phenyl} -acetamide, N- {4- [4- (2-pentylamino-ethyl) -phenoxy] -phenyl-acetamide, N- ( 4- {4- [2- (cyclohexylmethyl-amino) -ethyl] -p

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