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TREATMENT OF C1013G/CXCR4-ASSOCIATED WALDENSTROM'S MACROGLOBULINEMIA WITH AN ANTI-CXCR4 ANTIBODY
专利权人:
BRISTOL-MYERS SQUIBB COMPANY
发明人:
Irene M. Ghobrial,Aldo M. Roccaro,Josephine M. Cardarelli,Antonio Sacco
申请号:
US16271569
公开号:
US20200002428A1
申请日:
2019.02.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides a method for treating a subject afflicted with Waldenström's macroglobulinemia (WM) comprising administering to the subject a therapeutically effective amount of an antibody or an antigen-binding portion thereof that specifically binds to a CXCR4 receptor expressed on the surface of a WM cell. The disclosure also provides a therapeutic regimen for treating a patient afflicted with C1013G/CXCR4-associated WM.
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