METHODS FOR PREPARING PEG-HEMOGLOBIN CONJUGATES USING REDUCED REACTANT RATIOS

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专利权人:

发明人:

申请号：

EP11747978.2

公开号：

EP2539715A1

申请日:

2011.02.23

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates generally to methods for preparing polyethylene glycol (“PEG”) conjugated hemoglobin (“Hb”) using reduced reactant ratios. More specifically, the present invention relates to methods for preparing PEG conjugated Hb (“PEG-Hb”) with enhanced yield and purity.

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