Green, Luke,Ratni, Hasane,Naryshkin, Nikolai A.,Weetall, Marla L.
申请号:
NZ72500815
公开号:
NZ725008A
申请日:
2015.05.11
申请国别(地区):
NZ
年份:
2019
代理人:
摘要:
The present invention provides compounds of formula (I) as SMN2 gene splicing modulators for treating skeletal muscular atrophy, wherein A, R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.