The asymmetric derivatives in formula (1) have the property of anti Androgene. 1.1.1.1.1.2 the complainant claims that the State Party has violated Article 14, paragraph 1 (c), of the covenant, which provides that the complainant has the right to appeal to and appeal to the Supreme Court of appeal. Where each R and R is selected independently of the H and asphalt groups； Z is an integer from 0 to 3； and X is selected from the group consisting of O, s, s (or).SO832222,Nr,R1 is selected from the group H, hydrocarbon and cor, R is hydrogen or tar； ch8322 and CO； or Z is 0, then x can be n, and together with R1, it forms a heterocyclic ring selected from the group, including morphine, 1, 2, 4-triazol, imidazol and imidazol n-replicated； and R1,If the above-mentioned X-ring is not formed, an optional 3-7-member ring is selected from a group consisting of asphalt, alquenilo (per) haloaquilo, haloalquenilo, hydrocarbyl CN and a cathode, heteromorphic, crystalline or isomerized arilo, and replaced by 1-5 substitutes selected from a group of asphalt. Alcoxi, hydroxilo, halogen, (per) halide, CN, no.832222；COR COOR CONHR NRNHCOCF₃,NHCOR NHCONHR NHCOOR OCONHR NHSO R NHCSCHSR, SOR and SO₂R, where R is as defined above； RB is a heteroaromatic ring that has a 6-membered ring and is optionally substituted on one or more carbon atoms of the ring, whose members of ring 1 or 2 are N atoms and the other members of the ring are carbon atoms, or RB is an optionally substituted phenyl group, the RB substituent (s) are selected from the group consisting of alkyl, alkoxy, hydroxy, halogen, (per) haloalkyl, CN, NO₂,COR COOR NRNHCOCF₃,Nhcor, nhconhr, nhcoor, oconhr, conhr, R are there as mentioned before； nhcsch832323,Mr. R, sor and so83228r； Mr. R, Mr. R, as mentioned above, or if RB is an optional phenyl substitute, then the two substitutes can also be composed of carbon atoms and connected to it, a substituted or unreplaced isopropene or heteroaromatic ring； RA is an heteroaromatic single
