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compound, process for preparing compounds, and pharmaceutical composition
专利权人:
ABBOTT HEALTHCARE PRODUCTS B.V.
发明人:
BERNARD J. VA VLIET,JOSEPHUS H. M. LANGE
申请号:
BRPI0915083
公开号:
BRPI0915083A2
申请日:
2009.06.15
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
This invention concerns fluorinated 3,4-diaryl-4,5-dihydro-1H-pyrazole-1-carboxamidine derivatives as cannabinoid-CB1 receptor antagonists, methods for preparing these compounds, novel intermediates useful for the synthesis of said compounds, methods for the preparation of these intermediates, pharmaceutical compositions containing one or more of these dihydropyrazole derivatives as active ingredient, as well as the use of these pharmaceutical compositions for the treatment of obesity and obesity-related cardiovascular disorders, drug addiction, cognition deficits, liver fibrosis and inflammatory disorders. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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