Alan C. Rapraeger,DeannaLee M. Beauvais,Oisun Jung
申请号:
US15680423
公开号:
US20180086813A1
申请日:
2017.08.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A fusion peptides with sequences derived from the extracellular domain of syndecan-1 that inhibits VLA-4 and IGF-1R signaling are disclosed. The fusion peptides include an IGF-1R-binding segment having the amino acid sequence LPAGEGPKEGEAVVLPEVEPGLTAREQ (SEQ ID NO:1) and a VLA-4-binding segment having the amino acid sequence sequence DFTFETSGENTA (SEQ ID NO:2).