Temple University - Of The Commonwealth System of Higher Education
发明人:
Domenico Pratico
申请号：
US13826223
公开号：
US20130310421A1
申请日:
2013.03.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided is a method for the treatment and/or prevention of an amyloid beta amyloidosis in a subject comprising the step of administering to the subject an effective amount of a 5-lipoxygenase-activating protein (FLAP) antagonist. In preferred embodiments, the FLAP antagonist is MK-591, or a pharmaceutically acceptable salt thereof. Also provided is a method for decreasing or preventing the deposition of beta amyloid in the brain of a subject comprising the step of administering to a subject an effective amount of a FLAP antagonist. In preferred embodiments, the FLAP antagonist is MK-591, or a pharmaceutically acceptable salt thereof.
