Provided are: a multi-layered lamellar granule comprising a nucleating agent, a ceramide-containing artificial stratum corneum lipid lamellar layer which encases the nucleating agent and a polymer layer disposed on the artificial stratum corneum lipid lamellar layer and an external skin application composition comprising the same. The external skin application composition shows improved moisturizing and barrier repair capabilities when applied to the skin, which can be advantageously used in cosmetics and pharmaceuticals.本発明は多層ラメラ顆粒及びこれを含有する皮膚外用剤組成物に関するものであって、核剤、前記核剤上のセラミド含有擬似角質脂質ラメラ層、及び前記擬似角質脂質ラメラ層上の高分子層を含むことを特徴とし、このような本発明の多層ラメラ顆粒を含有する皮膚外用剤組成物は皮膚への塗布時に優れた保湿効果及び障壁機能の治癒効果を示す。