The present invention relates to 3-disubstituted indol-2-one derivatives of general formula (I):in which, R1, R2, R3, R4, R5, Ar and n are as defined in claim 1, to the process for preparing the said compounds and to the therapeutic application thereof.本發明係關於通式(I)之3-二取代吲哚-2-酮衍生物:其中、R1、R2、R3、R4、R5、Ar及n係如請求項1所定義,本發明亦關於製備該等化合物之方法以及其治療用途。