Ana Ramirez De Molina,Lourdes Garcia Oroz,Juan Carlos Lacal Sanjuan
申请号：
US13209220
公开号：
US20120040021A1
申请日:
2011.08.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to compositions comprising an acid ceramidase inhibitor and a choline kinase inhibitor as well as to the uses thereof for the treatment of cancer. The invention also relates to methods for the selection of an individualised therapy of a cancer patient based on the detection of the acid ceramidase levels. Moreover, the invention also relates to compositions comprising a choline kinase inhibitor and an alkylating agent and uses thereof for the treatment of cancer. Finally, the invention also relates to compositions comprising a choline kinase inhibitor and an alkylating agent or a death receptor ligand and uses thereof for the treatment of cancer.
