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Formulation of aspirin that is stable and showing minimal hydrolysis for parenteral administration for the treatment of cardiovascular and other disease states
专利权人:
John Charin Somberg
发明人:
John Charin Somberg,Vasant V Ranade
申请号:
US12454847
公开号:
US08481600B2
申请日:
2009.05.26
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed herein are ways to solubilize aspirin for parenteral administration containing aspirin and a diluent NNDMA (N,N-Dimethylacetamide) useful in the treatment of acute coronary syndromes as well as other disease states. The solution so constituted is stable at room temperature for prolonged periods without decomposition and avoids significant hydrolysis of the aspirin and thus the loss of the anti-platelet action when stored.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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