Paola Stefanelli,Alberto Scarsetto,Maurizio Di Grigoli,Pierbruno Romelli
申请号:
US14085334
公开号:
US20140080911A1
申请日:
2013.11.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a Tg lower than 0.degree. C., whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention allow to prepare therapeutical systems for the controlled-release of active principles through the transdermal route, thus solving stability, solubility and/or bioavailability problems of the active ingredient within the matrix.