Kevin PETERS,Mitchell BRIGELL,Stephen PAKOLA,Robert Shalwitz
申请号：
US16284349
公开号：
US20190262321A1
申请日:
2019.02.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with diabetic nephropathy, for example, diabetic nephropathy resulting from hyperglycemia, kidney hyperfiltration, renal injury, glycation products, and cytokine activation.
