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MÉTHODE DE PRÉDICTION D'EFFET CLINIQUE D'UNE IMMUNOTHÉRAPIE
专利权人:
INC.;INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY
发明人:
SUGIYAMA, HARUO,OJI, YUSUKE
申请号:
EP14797083
公开号:
EP2998740A4
申请日:
2014.05.12
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Provided is a method for predicting a clinical effect on a subject in a WT1 peptide immunotherapy, said method comprising: a) a step for contacting a sample derived from the subject with WT1 antigen peptide or a variant thereof; and b) a step for detecting the binding of the sample to the WT1 antigen peptide or a variant thereof and thus measuring anti-WT1 antigen peptide IgG antibody titer existing in the sample, characterized in that an increase in the anti-WT1 antigen peptide IgG antibody titer in the subject determines the achievement of a favorable clinical effect. Also provided is a kit for performing the method according to the present invention, said kit containing WT1 antigen peptide or a variant thereof.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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