LINHARDT, Jeffrey G.,NUNEZ, Ivan M.,MCGEE, Joseph A.,HUNT, Jennifer,ALTON, Michele,PAVLOVIC, Drazen,SHIPP, Devon A.
申请号：
ES10727306
公开号：
ES2564629T3
申请日:
2010.06.14
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
A contact lens comprises a polymerization product of a mixture comprising (a) one or more homopolymers containing siloxane comprising a thiocarbonylthio fragment of a reversible fragmentation chain additive (RAFT) agent； and (b) one or more monomers forming a biomedical device, where the homopolymer containing siloxane is of the general formula: ** Formula ** where L is a connecting group, R10 and R11 are independently hydrogen, a C1-C30 alkyl group linear or branched, a C1-C30 fluoroalkyl group, a C1-C20 ester containing group, an alkyl ether group, a cycloalkyl ether group, a cycloalkenyl ether group, an aryl ether group, an arylalkyl ether group, a C1- alkoxy group C30 substituted or unsubstituted, a substituted or unsubstituted C3-C30 cycloalkyl group, a substituted or unsubstituted C3-C30 cycloalkylalkyl group, a substituted or unsubstituted C3-C30 cycloalkenyl group, a substituted or unsubstituted C5-C30 aryl group, a substituted or unsubstituted C5-C30 arylalkyl group, a substituted or unsubstituted C5-C30 heteroaryl group, a substituted or unsubstituted C3-C30 heterocyclic ring, a substituted or unsubstituted C4-C30 heterocycloalkyl group, a hetero group C6-C30 substituted or unsubstituted alkyl, fluorine, a C5-C30 fluoroaryl group, a siloxy group, or a hydroxyl group； n is from 2 to 100, and A is a thiocarbonylthio fragment of the RAFT agent, where the one or more biomedical device forming monomers include a hydrophilic monomer selected from the group consisting of an unsaturated carboxylic acid, acrylamide, vinyl lactam, poly (alkyleneoxy) (meth) acrylate, (meth) acrylic acid, (meth) acrylate containing hydroxyl, hydrophilic vinyl carbonate, hydrophilic vinyl carbamate monomer, hydrophilic oxazolone monomer, and mixtures thereof.Una lente de contacto de comprende un producto de polimerización de una mezcla que comprende (a) uno o más homopolímeros que contienen siloxano que comprenden un fragmento de tiocarboniltio de un agente de transferencia de cadena p
