A medical fastening device (100) for fastening or coupling an object (400A, 400B) into a tissue (20) have proximal (100A) and distal (100B) portions. It also comprises a helical body structure (107), where the helical body structure comprises a thread or ridge (104) having a lead (105) between said proximal and distal portions. The helical body structure comprises a first portion (101/103) and a second portion (102) next to said first portion (101). The thread of the helical body structure advantageously extends through the first (101) and second (102) portions and the properties, such as a pitch and/or lead, of the thread vary along the longitudinal axis (106) of the helical body structure so that the property of the thread has a first value in the first portion (101) and a second value in the second portion (102) so to provide different compressive force to the object and/or tissue introduced in said first and second portions of the helical body structure, and wherein the first value differs from the second value.
