WALLING, John,JONAITIS, David T.,PARENT, Stephan D.,KRAL, Robert M.
申请号：
AU2015200516
公开号：
AU2015200516A1
申请日:
2015.02.03
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
#$%^&*AU2015200516A120150219.pdf#####ABSTRACT OF THE DISCLOSURE A triterpenoid compound, methyl 2-cyano-3,12-dioxoleana-1,9(11)-dien-28-oate (CDDO methyl ester), has a non-crystalline, glassy solid form and a non-hydrous crystalline form that can prepared, for example, from a saturated methanol solution. The glassy form displays an enhanced bioavailability over the non-hydrous crystalline form. Each form of CDDO methyl ester is a superior candidate for use, typically in solid dosage form, for treating a variety of disease states, generally associated with inflammation. 6149737_1 (GHMatters) P33272.AU.1 JBECKER 3-Feb-151/32 Figure 1 - Chemical structure of CDDO methyl ester RTA-402 0 NC CO2CH3 NCN C32H 43NO4 Mol. Wt.: 505.69
