Robert Wood,Hai-Quan Mao,Corinne Keet,Russell Martin
申请号:
US14400856
公开号:
US09539334B2
申请日:
2013.05.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides a thin mucoadhesive sublingual film composition which provides improved allergen delivery and efficacy at a smaller dose while prolonging the contact time between the allergen and oral antigen presenting cells (APCs), and therefore minimizing the risk of systemic side effects. The thin film compositions of the present invention are also easier to standardize, and removes any need for measuring allergen doses at the physicians office, and which allows for a simplified dosing schedule. Methods of making the thin film compositions and methods for their use are also disclosed.