PROBLEM TO BE SOLVED: To provide antipyretic analgesics which inhibit gastric disorder due to diclofenac sodium, etodolac, sulindac, meclofenamic acid, or salts thereof, have excellent efficacy, and have improved stability, ingestibility, and manufacturability.SOLUTION: The invention provides a pharmaceutical composition characterized by containing (a) diclofenac sodium, etodolac, sulindac, meclofenamic acid or salts and mixtures thereof, and (b) acetaminophen, the acetaminophen (b) being comprised in the amount of 1.5-7.5 parts by weight with respect to 1 part by weight of the component (a).SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】ジクロフェナクナトリウム、エトドラク、スリンダク、メクロフェナム酸、又はこれらの塩による胃障害を抑制し、有効性に優れ、ならびに安定性、服用性及び製造性が向上した解熱鎮痛薬を提供する。【解決手段】(a)ジクロフェナクナトリウム、エトドラク、スリンダク、メクロフェナム酸、またはその塩並びに混合物と、(b)アセトアミノフェンを含み、(a)成分1重量部に対して、(b)アセトアミノフェンを1.5~7.5重量部含むことを特徴とする医薬品組成物。【選択図】なし