Different serotypes of vesicular stomatitis virus as expression vectors for immunization

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专利权人:

ザ ユニバーシティー オブ ウェスタン オンタリオ

发明人:

カン，チル－ヨン,キム，ギュオン，ニョン,カン,チル-ヨン,キム,ギュオン,ニョン

申请号：

JP2012513426

公开号：

JP5675789B2

申请日:

2010.06.08

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

Immunization platforms, immunization regimes and medicaments useful for inducing an immune response in a mammal and preventing or treating a pathogenic infection in a mammal, wherein said immunization platforms and medicaments comprise a recombinant vesicular stomatitis virus (VSV) of one serotype and a rVSV of another serotype and are used in a prime-boost immunization regime. In aspects of the invention one VSV serotype is Indiana and the other VSV serotype is New Jersey.

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