Novel means and methods for treating malaria and other parasitic disorders

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专利权人:

发明人:

申请号：

EP12190851.1

公开号：

EP2727911A1

申请日:

2012.10.31

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention relates to a compound of formula (I)wherein X is NH or O Y is OH A is H or COOH B is H, CH2OH or CH2NH2 (a) ZR1R2 is isoquinolin-1-yl, said isoquinolin-1-yl being partially or fully hydrated in the N-containing ring or given by formula (II)or (b) Z is O or N R1 is (i) C1 to C6 alkyl, preferably CH3 C2 to C6 alkenyl or C2 to C6 alkynyl or (ii) arylalkyl, preferably phenylalkyl, alkyl in said arylalkyl being C1 to C4 alkyl, phenylalkyl preferably being CH2C6H5 R2 is (iii)absent in case of Z being O or (iv) H in case of Z being N.

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