The present invention concerns compounds of formula (I) a stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereof, wherein -a1=a2-a3=a4- is a bivalent radical wherein one or two of a1 to a4 are nitrogen and the remaining a1 to a4 are -CH- -Z1-Z2- is a bivalent radical -A- is a bivalent radical of formula -N(R6)-Alk2- or a 5, 6 or 7-membered saturated heterocycle containing one or two nitrogen atoms R1, R2 and R3 are each independently selected from hydrogen, C1-6alkyl, hydroxy, halo and the like Alk1 and Alk2 are optionally substituted C1-6alkanediyl R5 is a radical of formula wherein n is 1 or 2 p1 is 0, and p2 is 1 or 2 or p1 is 1 or 2, and p2 is 0 X is oxygen, sulfur or -NR9 Y2 is oxygen or sulfur R7 is hydrogen, C1-6alkyl, C3-6cycloalkyl, phenyl or phenylmethyl R8 is C1-6alkyl, C3-6cycloalkyl phenyl or phenylmethyl R9 is cyano, C1-6alkyl, C3-6cycloalkyl, C1-6alkyloxycarbonyl or aminocarbonyl R10 is hydrogen or C1-6alkyl and Q is a bivalent radical. Processes for preparing said products, formulations comprising said products and their use as a medicine are disclosed, in particular for treating conditions which are related to disturbed fundic accomodation.
