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Formes posologiques à libération contrôlée enchâssées et inviolables
专利权人:
Purdue Pharma L.P.
发明人:
申请号:
EP14186658.2
公开号:
EP2826467A1
申请日:
2011.12.21
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a core comprising a first portion of an opioid analgesic dispersed in a first matrix material comprising polyethylene oxide having an average molecular weight from about 300,000 to about 10,000,000; and a shell encasing the core and comprising a second portion of the opioid analgesic dispersed in a second matrix material comprising polyethylene oxide having an average molecular weight from about 1,000,000 to about 10,000,000.
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