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PROCEDE DE PRODUCTION D'UN COMPOSITE MEDICAMENT-COPOLYMERE SEQUENCE ET PRODUIT PHARMACEUTIQUE CONTENANT LEDIT COMPOSITE
专利权人:
NIPPON KAYAKU KABUSHIKI KAISHA
发明人:
MOTOYAMA, JUN
申请号:
CA2809934
公开号:
CA2809934C
申请日:
2011.08.31
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
[Problem] There has been a requirement for a process forproducing a pharmaceutical preparation that is obtained byencapsulating a uniform poorly water-soluble drug in a blockcopolymer, and dissolves immediately with an addition of water,and does not contain residues of organic solvents.[Solution] Provided is a method for producing a drug-blockcopolymer composite, the method comprising: mixing a poorlywater-soluble drug and a block copolymer including ahydrophilic segment and a hydrophobic segment bonded together,in one or more non-aqueous solvents; optionally heating themixture as necessary; and spray-drying the resulting mixtureliquid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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