Gary Huvard;Gurbhagat Sandhu;Kevin Ward;Everette Carpenter;Robert Barbee;Bruce Spiess
发明人:
Kevin Ward,Gary Huvard,Everette Carpenter,Gurbhagat Sandhu,Robert Barbee,Bruce Spiess
申请号:
US13372364
公开号:
US20120207793A1
申请日:
2012.02.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods and compositions for the controlled and sustained release of peroxides or oxygen to aqueous environments (e.g. a patient's body or circulatory system, or for other applications) or non-aqueous environments, include a material coating or encapsulating hydrogen peroxide, inorganic peroxides or peroxide adducts. In the case of peroxide adducts, and particularly in one type of embodiment, the peroxide adducts should be able to permeate the material, but water, hydrogen peroxide and inorganic peroxides should be able to permeate the material. The methods and compositions that allow the release of oxygen, H2O2 or inorganic peroxides from peroxide adducts with movement of these moieties across a selectively permeable barrier into, preferably, an aqueous environment. In the case of hydrogen peroxide, it can be acted upon by catalase or other enzymes, or be simply degraded, or are otherwise acted upon by enzymes or catalysts embedded in the selectively permeable barrier to produce, for example, O2. Alternatively, hydrogen peroxide or inorganic peroxides can be delivered selectively to a site of action of cleaning, disinfecting or other applications.