The present disclosure pertains to a system configured to determine a hemodynamic instability risk score for a pediatric subject. The system is configured to: obtain an age of the subject obtain feature values for one or more features associated with physiological characteristics of the subject determine one or more feature value thresholds for individual features that indicate risk of hemodynamic instability in the subject the feature value thresholds determined based on the age of the subject determine feature contribution prediction scores for the individual features based on whether the obtained feature values breach one or more of the determined feature value thresholds for the individual features and aggregate the feature contribution prediction scores to determine the hemodynamic instability risk score for the subject.
