The present Invention relates to pharmaceutical compositions that comprise a CRTH2 antagonist and at least a Histamine Receptor Antagonist Drug, Pharmaceutical compositions containing them, and to the use of said Pharmaceutical compositions for treating diseases and T Rastornos respiratory and inflammatory.La presente invención se refiere a composiciones farmacéuticas que comprenden un antagonista de CRTH2 y al menos un antagonista del receptor de histamina, a medicamentos que contienen dichas composiciones farmacéuticas, y al uso de dichas composiciones farmacéuticas para tratar enfermedades y trastornos respiratorios e inflamatorios.