The utility model relates to an endoscope instrument and a waterproof element thereof, which are used to solve the problem that the body fluid of the patient may contaminate the catheter during the inspection of the endoscope.The invention includes: a waterproof element, which is concave from an opening to form a compartment, a first joint is formed around the opening, the waterproof element is provided with a transparent part on the wall of the compartment, the transparent part is opposite to the opening along an axial direction; and an inspection module, which is provided with a conduit, which penetrates into the compartment from the opening, and two ends of the conduit are respectively provided with an image taking element And a second joint, the image pickup element facing the transparent part, and the second joint being combined with the first joint.Therefore, the invention has the effect of preventing the catheter from being polluted by the patient's body fluid.一種內視鏡儀器及其防水元件,用以解決內視鏡檢查時,病患之體液會汙染導管的問題。本創作係包含:一防水元件,係由一開口凹入形成一容室,該開口之周緣形成一第一結合部,該防水元件於該容室的壁面設有一透明部,該透明部與該開口沿一軸向相對;及一視察模組,具有一導管,該導管由該開口穿入該容室,該導管之二端分別設有一取像元件及一第二結合部,該取像元件朝向該透明部,該第二結合部結合於該第一結合部。藉此,本創作具有防止病患之體液汙染導管的功效。