PROBLEM TO BE SOLVED: To provide an organism tissue closure device which can independently perform holding operation by press-holding means and a puncture operation by a puncture part with respect to an organism tissue near a defect, in which the structure of hand operation part is simplified, and with which a manual treatment can be performed smoothly, safely, and reliably.SOLUTION: The organism tissue closure device, wherein the press-holding means K supplies current while organism tissues M each composed of an interatrial septum M1 and a valve of oval foramen M2 are held by a pressing portion 62 and press-held by press-holding means K, and the organism tissues M are joined to each other, is provided with a lock-unlock mechanism 102 for selectively performing either retention of a state that the holding part 62 holds the valve of oval foramen M2, or cancellation of the holding state.COPYRIGHT: (C)2010,JPO&INPIT【課題】欠損周辺の生体組織に対する挟圧手段による保持操作と穿刺部による穿刺操作とを独立に行なうことができ、手元操作部の構成を簡素化した、手技を円滑に、安全かつ確実に行うことができる生体組織閉鎖デバイスを提供する。【解決手段】心房中隔M1及び卵円孔弁M2からなる生体組織Mを保持部62で保持した後、挟圧手段Kにより挟持した状態で、挟圧手段Kに電流を流し、生体組織Mを相互に融着させる生体組織閉鎖デバイスに、保持部62が卵円孔弁M2を保持した状態と、この保持状態の解除とを選択的に行うロック-アンロック機構102を設けたことを特徴とする。【選択図】図3
