JIA, ZHAOZHONG J.,贾 照中,賈 照中,CHEN, WEI,陈伟,陳偉,THOMAS, WILLIAM D.,汤玛斯 威廉 D,湯瑪斯 威廉 D
申请号：
TW108121852
公开号：
TW201938549A
申请日:
2014.12.05
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
Disclosed herein are reversible and irreversible inhibitors of Bruton’s tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are describeded, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.本文揭示布魯頓氏酪胺酸激酶(Btk)之可逆及不可逆抑制劑。亦揭示包括該等化合物之醫藥組合物。描述使用該等Btk抑制劑，單獨或與其他治療劑組合，用於治療自體免疫疾病或病狀、異種免疫疾病或病狀、包括淋巴瘤之癌症及發炎性疾病或病狀的方法。
