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Solid form of pyrazolopyridine compound
专利权人:
SUNSHINE LAKE PHARMA CO.; LTD.
发明人:
Shouzhu Liao,Weijie Fan,Zhongqing Wang
申请号:
US15027432
公开号:
US09884859B2
申请日:
2014.10.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A novel crystalline form or amorphous of formula (I) and preparation method thereof are disclosed in present invention, wherein the novel crystalline form is substantially pure crystalline form I, form II, form III or form IV. The novel crystalline forms disclosed herein have good solubility, low hydroscopicity and good stability at high temperature (60° C.), high humidity (RH is 90%±5%) and/or under light (4500+/−500 Lux), which benefit for storage, meet the requirements of drug stability and therefore, making formula (I) suitable for formulation preparation and with high bioavailability.
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