A microneedle device comprising: a substrate 2 comprising one or more layers and at least one microneedle 1 which extends from the substrate 2 wherein the substrate 2 comprises at least one layer 4 which is a high surface energy material layer and which is capable of retaining the at least one microneedle 1. A method of manufacturing the microneedle device is also provided. The substrate 2 may further comprise an upper layer and a lower layer 5,6, and wherein the high surface energy material layer 4 is sandwiched between the upper and the lower layers 5,6. The microneedle 1 may be affixed to the substrate with an adhesive. The high surface energy material layer may be a plastic, metal, polymer, ceramic or a combination of one or more of these having a surface energy of from 250 to 1500 mJ/m2. The high surface energy layer may comprise stainless steel and may be a mesh.
