Method of regulating mammalian target-of-rapamycin activity by interaction between phospholipase D and raptor

• 收藏
• 分享

专利权人:

Sung-Ho Ryu

发明人:

Sung-Ho Ryu,Pann-Ghill Suh,Sang-Hoon Ha,Do-Hyung Kim,Il-Shin Kim,Jung-Hwan Kim,Mi-Nam Lee,Hyun-Ju Lee,Jong Heon Kim,Sung-Key Jang,Tae-Hoon Lee

申请号：

US12374262

公开号：

US08278263B2

申请日:

2007.08.03

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to a method of regulating mammalian target-of-rapamycin (mTOR) by regulating a phospholipase D (PLD) activity that generates a complex with mTOR. Further, the present invention also relates to a method of screening inhibitors of mTOR, and a method and a composition for treating mTOR-related metabolic diseases by inhibiting mTOR.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/