Gregory P. Chang,Ann F. Cheung,Jinyan Du,Asya Grinberg,William Haney,Dhruv Kam Sethi,Nicolai Wagtmann,Bradley M. Lunde,Bianka Prinz
申请号:
US16638559
公开号:
US20200216544A1
申请日:
2018.08.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Multi-specific binding proteins that bind NKG2D receptor, CD16, and a tumor-associated antigen selected from EGFR, HLA-E, CCR4, and PD-L1 are described, as well pharmaceutical compositions and therapeutic methods useful for the treatment of cancer.