methods and compositions for the treatment of diabetes and dyslipidemia. The present invention relates to novel compounds of formula I: stereoisomers and / or pharmaceutically acceptable salts thereof for the treatment of diabetes and diabetes-associated dyslipidemia, wherein R1 is selected from the group consisting of hydroxy, alkoxy amine, alkyl, haloalkyl, nso-2r, or nr wherein r is selected from alkyl or cycloalkyl, wherein r is alkyl or cycloalkyl optionally substituted by hydroxy or alkoxy； en ^ 1 ^ en ^ 2 ^ are independently selected from 0, 1 and 2. at least one of r ^ 3 ^ er ^ 4 ^ and / or r ^ 5 ^ er ^ 6 ^ forms a cyclic ring of 3 to 8 atoms which optionally contain alkyl groups, heteroatoms, functional groups such as o, n, so ~ 2 ~. furthermore, when r3 or r5 and r6 do not form a cyclic ring, then they may be independently selected from hydrogen, alkyl, branched alkyl and cycloalkyl. 1-1 is a linear aliphatic chain optionally containing from 4 to 16 carbon atoms. the chain may optionally be substituted one or more times by branched alkyl, cycloalkyl or aryl. R2 is independently selected from hydrogen, alkoxy, hydroxy, aquyl, haloalkyl, cycloalkyl, heterocycloalkyl, heteroaryl, cyano, or color wherein R2 is selected from hydroxy, alkyl, alkoxy, or amine, nhr , neither ~ 2 ~ r or nhcor. Y1 is oxygenated or hydrogen. y ^ 2 ^ is optional, wherein when y ^ 2 ^ is optional wherein when y ^ 2 ^ is present, y ^ 1 ^ and y ^ 2 ^ are hydrogen. when y ^ 2 ^ is not present, y ^ 1 ^ is a carbonyl group.métodos e composições para o tratamento de diabetes e dislipidemia. a presente invenção refere-se a novos compostos da fórmula i: seus estereoisômeros e/ou sais farmaceuticamente aceitáveis para o tratamento de diabetes e de dislipidemia associada com o diabetes, em que r^ 1^ é selecionado do grupo que consiste em hidróxi, alcóxi, amina, alquila, haloalquila, nhso~ 2r, ou nhcor que r é selecionado de alquila ou cicloalquila, nhr em que r é alquila ou cicloalquila opcional
