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DERIVATIZED 3-STYRYL-CEPHALOSPORINS
专利权人:
发明人:
申请号:
EP14778768.3
公开号:
EP2968352A2
申请日:
2014.03.12
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making betalactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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