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Anhydrous Depigmenting Compositions Containing a Solubilized Phenolic Derivative and Retinoid in the Fat Component
专利权人:
ГАЛДЕРМА РЕСЕРЧ ЭНД ДЕВЕЛОПМЕНТ (FR)
发明人:
МАЛЛАР Клер (FR),НАДО-ФУРКАД Карин (FR),ЛУИ Фабьенн (FR)
申请号:
RU2010153985/15
公开号:
RU2010153985A
申请日:
2009.06.02
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. Anhydrous pharmaceutical composition comprising:! a) a phenolic derivative selected from hydroquinone, rucinol or lucinol and their salts, 4-hydroxyanisole, hydroquinone monoethyl ether and hydroquinone monobenzyl ether; ! b) a retinoid; ! characterized in that the phenolic derivative and retinoid are solubilized and / or dispersed in the fat component of the composition. ! 2. The composition according to claim 1, characterized in that the phenolic derivative is solubilized in at least one fat component of the composition. ! 3. The composition according to claim 1 or 2, characterized in that the retinoid is solubilized in at least one fat component of the composition. ! 4. The composition according to claim 1 or 2, characterized in that the retinoid is dispersed in at least one fat component of the composition. ! 5. The composition according to claim 4, characterized in that the fat component contains an oil ingredient that dissolves the phenolic derivative. ! 6. The composition according to claim 5, characterized in that the oil component dissolving the phenolic derivative contains an oil solvent and / or lipophilic surfactant. ! 7. The composition according to claim 5, characterized in that the solvent oil component is selected from esters and their derivatives, ethers and their derivatives and triglycerides of caprylic and capric acids. ! 8. The composition according to claim 6, characterized in that the lipophilic surfactant is a caprylic and capric acid PEG-8 triglyceride. ! 9. The composition according to claim 4, characterized in that it contains an oil component dispersing a retinoid. ! 10. The composition according to claim 9, characterized in that the dissolving oil component dispersing a retinoid,1. Безводная фармацевтическая композиция, содержащая: ! a) фенольное производное, выбранное из гидрохинона, руцинола или луцинола и их солей, 4-гидроксианизола, моноэтилового эфира гидрохинона и монобензилового эфира гидрохинона; ! b) ретиноид; ! отличающая
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